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Anti-eniyan IL6, Mouse Monoclonal

Apejuwe kukuru:

Ìwẹnumọ Affinity-chromatography Isotype Ko Ṣe ipinnu
Ogun Eya Asin Eya Reactivity Eniyan
Ohun elo Chemiluminescent Immunoassay (CLIA)/ Immunochromatography (IC)

Alaye ọja

ọja Tags

Awọn alaye ọja

Ifihan pupopupo
Interleukin-6 (IL-6) jẹ cytokine α-helical multifunctional ti o ṣe ilana idagbasoke sẹẹli ati iyatọ ti awọn oriṣiriṣi awọn tisọ, eyiti a mọ ni pataki fun ipa rẹ ninu esi ajẹsara ati awọn aati alakoso nla.Amuaradagba IL-6 ti wa ni ikọkọ nipasẹ ọpọlọpọ awọn iru sẹẹli pẹlu awọn sẹẹli T ati awọn macrophages bi phosphorylated ati moleku glycosylated ti o yatọ.O ṣe awọn iṣe nipasẹ olugba heterodimeric rẹ ti o ni IL-6R ti ko ni agbegbe tyrosine/kinase ati sopọ IL-6 pẹlu isunmọ kekere, ati glycoprotein 130 (gp130) ti o ṣafihan ni gbogbo ibi ti o sopọ mọ IL-6.IL-6R eka pẹlu ga ijora ati bayi transduces awọn ifihan agbara.IL-6 tun ṣe alabapin ninu hematopoiesis, iṣelọpọ eegun, ati ilọsiwaju alakan, ati pe a ti ṣalaye bi ipa pataki ninu didari iyipada lati innate si ajesara ti o gba.

Awọn ohun-ini

Iṣeduro bata CLIA (Iwa-iṣawari):
1B1-4 ~ 2E4-1
2E4-1 ~ 1B1-4
Mimo > 95%, ipinnu nipasẹ SDS-PAGE
Ifipamọ Fọọmù PBS, pH7.4.
Ibi ipamọ Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba.
Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ.

Ifiwera Idije

Itupalẹ ibamu-<120pg>

alaye (1)

Iṣiro ibamu -1.5-5000pg/ml

alaye (2)

Bere fun Alaye

Orukọ ọja Ologbo.Rara ID oniye
IL6 AB0001-1 1B1-4
AB0001-2 2E4-1
AB0001-3 2C3-1

Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.

Awọn itọkasi

1.Zhong Z, Darnell ZW, Jr. Stat3: ọmọ ẹgbẹ ẹbi STAT ti a mu ṣiṣẹ nipasẹ phosphorylation tyrosine ni idahun si ifosiwewe idagba epidermal ati interleukin-6 [J].Imọ-jinlẹ, ọdun 1994.

2.J, Bauer, F, et al.Interleukin-6 ni oogun iwosan [J].Awọn itan ti Hematology, 1991.


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