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Anti-eniyan MPO Antibody, Mouse Monoclonal

Apejuwe kukuru:

Ìwẹnumọ Affinity-chromatography Isotype Ko Ṣe ipinnu
Ogun Eya Asin Eya Reactivity Eniyan
Ohun elo Immunochromatography (IC)/Chemiluminescent Immunoassay (CLIA)/Turbidimetric Latex

Alaye ọja

ọja Tags

Awọn alaye ọja

Ifihan pupopupo
MPO (myeloperoxidase) jẹ enzymu peroxidase ti a fi pamọ nipasẹ awọn leukocytes ti a mu ṣiṣẹ ti o ṣe ipa pathogenic ninu arun inu ọkan ati ẹjẹ, nipataki nipasẹ ipilẹṣẹ ailagbara endothelial.Myeloperoxidase (MPO) jẹ enzymu ti o ṣe pataki, eyiti o jẹ ọkan ninu awọn paati ti eto antibacterial ni neutrophils ati monocytes.MPO ṣe alabapin ninu idahun iredodo ni awọn ipo pupọ ninu ara, pẹlu awọn keekeke ti mammary.Myeloperoxidase (MPO), enzymu leukocyte polymorphonuclear kan pato, ti lo ni iṣaaju lati ṣe iwọn nọmba awọn neutrophils ninu àsopọ.Iṣẹ MPO ni a rii ni laini ibatan si nọmba awọn sẹẹli neutrophili.Eto MPO ṣe ipa pataki ninu iṣakoso awọn akoran ati piparẹ awọn sẹẹli buburu.Sibẹsibẹ, awọn iyipada ninu eto MPO le ja si ibajẹ DNA ati carcinogenesis.Awọn polymorphisms ninu jiini MPO ti ni nkan ṣe pẹlu ikosile ti MPO ti o pọ si ati eewu ti o ga julọ fun idagbasoke alakan.Myeloperoxidase (MPO) jẹ ọkan ninu awọn antigens afojusun pataki ti antineutrophil cytoplasmic autoantibodies (ANCA) ti a rii ni awọn alaisan ti o ni vasculitis-ọkọ kekere ati Pauci-immune necrotizing glomerulonephritis.Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) jẹ ẹya autoantibody ti a rii nigbagbogbo ni awọn alaisan pẹlu vasculitides.

Awọn ohun-ini

Iṣeduro bata  
CLIA (Iwa-iṣawari):
4D12-3 ~ 2C1-8
4C16-1 ~ 2C1-8
Mimo > 95%, ipinnu nipasẹ SDS-PAGE
Ifipamọ Fọọmù PBS, pH7.4.
Ibi ipamọ Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba.
Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ.

Ifiwera Idije

alaye (1)
alaye (2)

Bere fun Alaye

Orukọ ọja Ologbo.Rara ID oniye
MPO AB0007-1 2C1-8
AB0007-2 4D12-3
AB0007-3 4C16-1

Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.

Awọn itọkasi

1.Klebanoff, S. J.Myeloperoxidase: ọrẹ ati ọta [J].J Leukoc Biol, 2005, 77 (5): 598-625.

2.Baldus, S. Myeloperoxidase Awọn ipele Serum Ṣe asọtẹlẹ Ewu ninu Awọn alaisan Pẹlu Awọn Aisan Arun Arun Arun Kokoro[J].Ayika, 2003, 108 (12): 1440.


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