Ifihan pupopupo
S100B jẹ amuaradagba abuda kalisiomu, eyiti o pamọ lati awọn astrocytes.O jẹ amuaradagba cytosolic dimeric kekere (21 kDa) ti o ni awọn ẹwọn ββ tabi αβ.S100B ṣe alabapin ninu ọpọlọpọ awọn iṣẹ ilana intracellular ati extracellular.
Ninu ewadun to koja, S100B ti farahan bi oludije agbeegbe biomarker ti ibajẹ-ọpọlọ ẹjẹ-ọpọlọ (BBB) ati ipalara CNS.Awọn ipele S100B ti o ga ni deede ṣe afihan niwaju awọn ipo neuropathological pẹlu ipalara ori ọgbẹ ati awọn aarun neurodegenerative.Awọn ipele S100B deede ni igbẹkẹle yọkuro pataki Ẹkọ aisan ara CNS.Omi ara S100B tun ti royin bi ami ami iwulo fun wiwa ni kutukutu ti awọn metastases ti melanoma ati awọn ilolu ọpọlọ lati ipalara ori, iṣẹ abẹ ọkan, ati ikọlu nla.
Iṣeduro bata | CLIA (Iwa-iṣawari): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
Mimo | > 95% gẹgẹbi ipinnu nipasẹ SDS-PAGE. |
Ifipamọ Fọọmù | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Orukọ ọja | Ologbo.Rara | ID oniye |
s100 β | AB0061-1 | 5H2-3 |
AB0061-2 | 22G7-5 | |
AB0061-3 | 21A6-1 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
1. Ostendorp T, Leclerc E, Galichet A, et al.Awọn oye igbekalẹ ati iṣẹ ṣiṣe sinu imuṣiṣẹ RAGE nipasẹ multimeric S100B[J].Iwe akosile EMBO, 2007, 26 (16): 3868-3878.
2. R, D, Rothoerl, et al.Awọn ipele S100B omi ara ti o ga fun awọn alaisan ti o ni ipalara laisi awọn ipalara ori.[J].Iṣẹ abẹ Neuro, ọdun 2001.