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Anti- PIVKA -II Antibody, Mouse Monoclonal

Apejuwe kukuru:

Ìwẹnumọ Amuaradagba A/G ijora ọwọn Isotype IgG1 kappa
Ogun Eya Asin Awọn Eya Antijeni Eniyan
Ohun elo Imunochromatography(IC)/Kemiluminescent Ajẹsara ajẹsara(CLIA)

Alaye ọja

ọja Tags

Ifihan pupopupo

Amuaradagba Ti a fa nipasẹ Vitamin K isansa tabi Antagonist-II (PIVKA-II), ti a tun mọ ni Des-γ-carboxy-prothrombin (DCP), jẹ ẹya ajeji ti prothrombin.Ni deede, awọn iṣẹku glutamic acid 10 prothrombin (Glu) ni agbegbe γ-carboxyglutamic acid (Gla) ni awọn ipo 6, 7, 14, 16, 19, 20,25, 26, 29 ati 32 jẹ γ-carboxylated si Gla nipasẹ Vitamini. -K ti o gbẹkẹle γ- glutamyl carboxylase ninu ẹdọ ati lẹhinna pamọ sinu pilasima.Ninu awọn alaisan ti o ni carcinoma hepatocellular (HCC), γ-carboxylation ti prothrombin ti bajẹ nitori pe PIVKA-II ti ṣẹda dipo prothrombin.PIVKA-II ni a gba bi o ṣe jẹ ami-ami biomarker daradara kan pato fun HCC.

Awọn ohun-ini

Iṣeduro bata CLIA (Iwa-iṣawari):

1E5 ~ 1D6

1E5 ~ 1E6

Mimo > 95%, ipinnu nipasẹ SDS-PAGE
Ifipamọ Fọọmù 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Ibi ipamọ Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba.Fun ibi ipamọ igba pipẹ, jọwọ ṣabọ ki o tọju rẹ.Yago fun didi leralera ati awọn iyipo thawing.

Ifiwera Analysis

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Bere fun Alaye

Orukọ ọja Ologbo.Rara ID oniye
PIVKA- AB0009-1 1F4
AB0009-2 1E5
AB0009-3 1D6
AB0009-4 1E6

Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.

Awọn itọkasi

1.Matsueda K, Yamamoto H, Yoshida Y, et al.Ẹjẹ ẹdọforo ti oronro ti n ṣe amuaradagba ti o fa nipasẹ isansa Vitamin K tabi antagonist II (PIVKA-II) ati α-fetoprotein (AFP) [J].Iwe akosile ti Gastroenterology, 2006, 41 (10): 1011-1019.

2.Viggiani, Valentina, Palombi, 等.Amuaradagba ti o fa nipasẹ isansa Vitamin K tabi antagonist-II (PIVKA-II) pọ si ni pataki ni awọn alaisan hepatocellular ti Ilu Italia.[J].Iwe akọọlẹ Scandinavian ti Gastroenterology, 2016.

3.Simundic AM.Awọn iṣeduro to wulo fun iṣiro iṣiro ati igbejade data ninu iwe iroyin Biochemia Medica[J].Biochemia Medica, 2012, 22 (1).

4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Amuaradagba ti a fa nipasẹ Vitamin K Isasasi II (PIVKA-II) bi ami-ara biomarker ti o pọju ninu akàn pancreatic: iwadii awaoko [J].Biochemia Medica, 2019, 29(2).


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