Ifihan pupopupo
Alpha-fetoprotein (AFP) jẹ ipin gẹgẹbi ọmọ ẹgbẹ ti superfamily albuminoid pupọ ti o ni albumin, AFP, Vitamin D (Gc) amuaradagba, ati alpha-albumin.AFP jẹ glycoprotein ti 591 amino acids ati ohun elo carbohydrate kan.AFP jẹ ọkan ninu ọpọlọpọ awọn ọlọjẹ-pato oyun ati pe o jẹ amuaradagba omi ara ti o ni agbara ni kutukutu igbesi aye ọmọ inu eniyan bi oṣu kan, nigbati albumin ati transferrin wa ni iwọn kekere.O jẹ iṣakojọpọ akọkọ ninu eniyan nipasẹ apo yolk sac ati ẹdọ (osu 1-2) ati lẹhinna ni pataki ninu ẹdọ.Iwọn kekere ti AFP jẹ iṣelọpọ nipasẹ ọna GI ti imọran eniyan.O ti fihan pe AFP le tun han ninu omi ara ni awọn iye ti o ga ni igbesi aye agbalagba ni ajọṣepọ pẹlu awọn ilana isọdọtun deede ati pẹlu idagbasoke buburu.Alpha-fetoprotein (AFP) jẹ ami kan pato fun carcinoma hepatocellular (HCC), teratoblastomas, ati abawọn tube neural (NTD).
Iṣeduro bata | CLIA (Iwa-iṣawari): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
Ifipamọ Fọọmù | PBS, pH7.4. |
Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20℃si -80℃lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Orukọ ọja | Ologbo.Rara | ID oniye |
AFP | AB0069-1 | 11D1-2 |
AB0069-2 | 3C8-6 | |
AB0069-3 | 8A3-7 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
1.Mizejewski GJ.(2001) Ilana Alpha-fetoprotein ati Iṣe: Ibaramu si Awọn Isoforms, Awọn Epitopes, ati Awọn iyatọ Ayipada.Exp Biol Med.226 (5): 377-408.
2.Tomasi TB, et al.(1977) Ilana ati iṣẹ ti Alpha-Fetoprotein.Lododun Review of Medicine.28: 453-65.
3.Leguy MC, et al.(2011) Igbelewọn ti AFP ni omi amniotic: lafiwe ti awọn ilana adaṣe adaṣe mẹta.Ann Biol Clin.69 (4): 441-6.