Anti- eda eniyan CHI3L1 Antibody, eda eniyan Monoclonal
Awọn alaye ọja
Ifihan pupopupo
Chitinase-3-like protein 1 (CHI3L1) jẹ heparin-binding glycoprotein ti a fi pamọ ti ikosile rẹ ni nkan ṣe pẹlu iṣipopada sẹẹli isan iṣan ti iṣan.CHI3L1 jẹ afihan ni awọn ipele giga ni awọn aṣa VSMC nodular postconfluent ati ni awọn ipele kekere ni awọn aṣa imugboroja subconfluent.CHI3L1 jẹ ihamọ-ihamọ-ara, chitin-abuda lectin ati ọmọ ẹgbẹ ti idile glycosyl hydrolase 18. Ni idakeji si ọpọlọpọ awọn ami ami monocyto / macrophage miiran, ikosile rẹ ko si ni awọn monocytes ati induced lagbara lakoko awọn ipele pẹ ti iyatọ macrophage eniyan.Awọn ipele ti o ga ti CHI3L1 ni nkan ṣe pẹlu awọn rudurudu ti n ṣafihan iyipada ti ara asopọ pọ si, gẹgẹbi rheum atoid, arthritis, osteoarthritis, scleroderma, ati cirrhosis ti ẹdọ, ṣugbọn ti a ṣe ni kerekere lati awọn oluranlọwọ atijọ tabi awọn alaisan pẹlu osteoarthritis.CHI3L1 jẹ aiṣedeede kosile ni hippocampus ti awọn koko-ọrọ pẹlu schizophrenia ati pe o le ni ipa ninu idahun cellular si ọpọlọpọ awọn iṣẹlẹ ayika ti o royin lati mu eewu schizophrenia pọ si.
Awọn ohun-ini
| Iṣeduro bata | CLIA (Iwa-iṣawari): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
| Ifipamọ Fọọmù | PBS, pH7.4 |
| Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Fun ibi ipamọ igba pipẹ, jọwọ ṣabọ ki o tọju rẹ.Yago fun didi leralera ati awọn iyipo thawing. |
Ifiwera Analysis
| Bioantibody | isẹgun ayẹwo irú | Lapapọ | |
| rere | Odi | ||
| rere | 46 | 3 | 49 |
| Odi | 4 | 97 | 101 |
| Lapapọ | 50 | 100 | 150 |
| atọka igbelewọn | ifamọ | pato | išedede |
| 92% | 97% | 95% | |
Bere fun Alaye
| Orukọ ọja | Ologbo.Rara | ID oniye |
| CHI3L1 | AB0031-1 | 1G11-14 |
| AB0031-2 | 2E4-2 | |
| AB0031-3 | 3A12-1 | |
| AB0031-4 | 13F3-1 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
Awọn itọkasi
1.Kyrgios I, Galli-Tsinopoulou A, Stylianou C, et al.Awọn ipele kaakiri ti o ga ti omi ara amuaradagba-fase YKL-40 (amuaradagba 3-like chitinase 1) jẹ ami isanraju ati resistance insulin ni awọn ọmọde prepubertal[J].Metabolism-isẹgun & Experimement, 2012, 61 (4): 562-568.
2.Yu-Huan M, Li-Ming T, Jian-Ying LI, ati al.Igbelewọn lori ohun elo omi ara chitinase-3-bii amuaradagba 1, alpha-fetoprotein ati wiwa ferritin lati ṣe iwadii aisan carcinoma hepatocellular hepatocellular[J].Oogun Idena Ise, 2018.
