Anti- PIVKA -II Antibody, Mouse Monoclonal
Ifihan pupopupo
Amuaradagba Ti a fa nipasẹ Vitamin K isansa tabi Antagonist-II (PIVKA-II), ti a tun mọ ni Des-γ-carboxy-prothrombin (DCP), jẹ ẹya ajeji ti prothrombin.Ni deede, awọn iṣẹku glutamic acid 10 prothrombin (Glu) ni agbegbe γ-carboxyglutamic acid (Gla) ni awọn ipo 6, 7, 14, 16, 19, 20,25, 26, 29 ati 32 jẹ γ-carboxylated si Gla nipasẹ Vitamini. -K ti o gbẹkẹle γ- glutamyl carboxylase ninu ẹdọ ati lẹhinna pamọ sinu pilasima.Ninu awọn alaisan ti o ni carcinoma hepatocellular (HCC), γ-carboxylation ti prothrombin ti bajẹ nitori pe PIVKA-II ti ṣẹda dipo prothrombin.PIVKA-II ni a gba bi o ṣe jẹ ami-ami biomarker daradara kan pato fun HCC.
Awọn ohun-ini
| Iṣeduro bata | CLIA (Iwa-iṣawari): 1E5 ~ 1D6 1E5 ~ 1E6 |
| Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
| Ifipamọ Fọọmù | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba.Fun ibi ipamọ igba pipẹ, jọwọ ṣabọ ki o tọju rẹ.Yago fun didi leralera ati awọn iyipo thawing. |
Ifiwera Analysis
Bere fun Alaye
| Orukọ ọja | Ologbo.Rara | ID oniye |
| PIVKA-Ⅱ | AB0009-1 | 1F4 |
| AB0009-2 | 1E5 | |
| AB0009-3 | 1D6 | |
| AB0009-4 | 1E6 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
Awọn itọkasi
1.Matsueda K, Yamamoto H, Yoshida Y, et al.Ẹjẹ ẹdọforo ti oronro ti n ṣe amuaradagba ti o fa nipasẹ isansa Vitamin K tabi antagonist II (PIVKA-II) ati α-fetoprotein (AFP) [J].Iwe akosile ti Gastroenterology, 2006, 41 (10): 1011-1019.
2.Viggiani, Valentina, Palombi, 等.Amuaradagba ti o fa nipasẹ isansa Vitamin K tabi antagonist-II (PIVKA-II) pọ si ni pataki ni awọn alaisan hepatocellular ti Ilu Italia.[J].Iwe akọọlẹ Scandinavian ti Gastroenterology, 2016.
3.Simundic AM.Awọn iṣeduro to wulo fun iṣiro iṣiro ati igbejade data ninu iwe iroyin Biochemia Medica[J].Biochemia Medica, 2012, 22 (1).
4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Amuaradagba ti a fa nipasẹ Vitamin K Isasasi II (PIVKA-II) bi ami-ara biomarker ti o pọju ninu akàn pancreatic: iwadii awaoko [J].Biochemia Medica, 2019, 29(2).
