Anti-eda eniyan SHBG Antibody, Mouse Monoclonal
Awọn alaye ọja
Ifihan pupopupo
Ibalopo homonu abuda globulin (SHBG) jẹ glycoprotein ti o to 80-100 kDa;o ni ibaramu giga fun awọn homonu beta-hydroxysteroid 17 gẹgẹbi testosterone ati estradiol.SHBG
ifọkansi ni pilasima jẹ ilana nipasẹ, laarin awọn ohun miiran, iwọntunwọnsi androgen/estrogen, awọn homonu tairodu, hisulini ati awọn okunfa ounjẹ.O jẹ amuaradagba gbigbe ti o ṣe pataki julọ fun awọn estrogens ati androgens ninu ẹjẹ agbeegbe.Idojukọ SHBG jẹ ifosiwewe pataki ti n ṣakoso pinpin wọn laarin amuaradagba ati awọn ipinlẹ ọfẹ.Awọn ifọkansi SHBG Plasma jẹ
fowo nipasẹ awọn nọmba kan ti o yatọ si arun, ga iye ti wa ni ri ni hyperthyroidism, hypogonadism, androgen insensitivity ati ẹdọ cirrhosis ninu awọn ọkunrin.Awọn ifọkansi kekere ni a rii ni myxoedema, hyperprolactinemia ati awọn iṣọn-ara ti iṣẹ-ṣiṣe androgen ti o pọ ju.Wiwọn SHBG jẹ iwulo ninu igbelewọn awọn rudurudu kekere ti iṣelọpọ androgen ati pe o jẹ ki idanimọ ti awọn obinrin wọnyẹn ti o ni hirsutism ti o ṣee ṣe diẹ sii lati dahun si itọju estrogen.
Awọn ohun-ini
| Iṣeduro bata | CLIA (Iwa-iṣawari): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
| Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
| Ifipamọ Fọọmù | PBS, pH7.4. |
| Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Ifiwera Idije
Bere fun Alaye
| Orukọ ọja | Ologbo.Rara | ID oniye |
| SHBG | AB0030-1 | 3A10-5 |
| AB0030-2 | 3E10-1 | |
| AB0030-3 | 3D8-2 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
Awọn itọkasi
1. Selby C. Ibalopo homonu abuda globulin: ipilẹṣẹ, iṣẹ ati pataki isẹgun.Ann Clin Biochem 1990; 27: 532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.IwUlO isẹgun ti homonu ibalopo abuda wiwọn globulin.Horm Res 1996; 45 (3-5): 148-155.
