Anti-eniyan RBP4 Antibody, Mouse Monoclonal
Awọn alaye ọja
Ifihan pupopupo
Retinol-abuda amuaradagba 4 (RBP4) jẹ awọn ti ngbe pato fun retinol (tun mo bi Vitamin A), ati ki o jẹ lodidi fun awọn iyipada ti riru ati insoluble retinol ni olomi ojutu sinu idurosinsin ati tiotuka eka ni pilasima nipasẹ wọn ju ibaraenisepo.Gẹgẹbi ọmọ ẹgbẹ ti superfamily lipocalin, RBP4 ti o ni eto β-barrel kan pẹlu iho asọye daradara ti wa ni ikoko lati ẹdọ, ati ni titan n gba retinol lati awọn ile itaja ẹdọ si awọn iṣan agbeegbe.Ni pilasima, eka RBP4-retinol ṣe ajọṣepọ pẹlu transthyretin (TTR), ati pe abuda yii ṣe pataki fun idilọwọ iyọkuro RBP4 nipasẹ glomeruli kidinrin.RBP4 ti a fihan lati orisun ectopic daradara n pese retinol si awọn oju, ati aipe rẹ yoo ni ipa lori iran alẹ pupọ.Laipe, RBP4 bi adipokine, ni a ri pe o han ni adipose tissue ati ni ibamu pẹlu isanraju, resistance insulin (IR) ati iru 2 diabetes (T2DM).
Awọn ohun-ini
| Iṣeduro bata | CLIA (Iwa-iṣawari): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Mimo | > 95% gẹgẹbi ipinnu nipasẹ SDS-PAGE. |
| Ifipamọ Fọọmù | PBS, pH7.4. |
| Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Ifiwera Idije
Bere fun Alaye
| Orukọ ọja | Ologbo.Rara | ID oniye |
| RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
Awọn itọkasi
1.Aiwei YB, Vijayalakshmi V, Bodles AM, et al.Retinol abuda amuaradagba 4 ikosile ninu eniyan: ibatan si resistance insulin, igbona, ati idahun si pioglitazone.[J].J Clin Endocrinol Metab (7): 2590-2597.
2.Haider DG, Karin S, Gerhard P, et al.Omi ara retinol-abuda amuaradagba 4 dinku lẹhin àdánù làìpẹ ni morbidly sanra koko.[J].Iwe akosile ti Clinical Endocrinology & Metabolism (3): 1168-71.
