Ifihan pupopupo
Pepsinogen I, awọn iṣaju ti pepsin, jẹ iṣelọpọ nipasẹ mucosa inu ti a si tu silẹ sinu lumen inu ati agbegbe agbegbe.Pepsinogen ni pq polypeptide kan ti 375 amino acids pẹlu aropin molikula ti 42 kD.PG I (isoenzyme 1-5) ti wa ni ikọkọ nipataki nipasẹ awọn sẹẹli olori ni mucosa fundic, lakoko ti PG II (isoenzyme 6-7) ti wa ni ikoko nipasẹ awọn keekeke pyloric ati mucosa duodenal isunmọ.
Precursor ṣe afihan awọn nọmba ti awọn sẹẹli oju inu ikun bi daradara bi awọn sẹẹli glandular, ati ṣe abojuto atrophy ikun ni aiṣe-taara.Wọn tun jẹ iduroṣinṣin lainidi nitori wọn ṣe awọn iṣẹ wọn labẹ awọn ipo lile ti o wa ninu eto ounjẹ.Atrophy ti mucosa corpus yori si iṣelọpọ kekere ti pepsinogen I ati nitorinaa itusilẹ kekere rẹ sinu omi ara.Omi ara pepsinogen I tọkasi iṣẹ ati awọn ipo ti mukosa inu.
Iṣeduro bata | CLIA (Iwa-iṣawari): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
Ifipamọ Fọọmù | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Orukọ ọja | Ologbo.Rara | ID oniye |
PGI | AB0005-1 | 1C1-3 |
AB0005-2 | 1E3-1 | |
AB0005-3 | 1G7-3 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
1.Sipponen P, Ranta P, Helske T, et al.Awọn ipele omi ara ti amided gastrin-17 ati pepsinogen I ni atrophic gastritis: iwadi-iṣakoso ọran akiyesi.[J].Scandinavian Journal of Gastroenterology, 2002, 37 (7): 785-791.
2.Mangla JC, Schenk EA, Desbaillets L, et al.Isọjade Pepsin, pepsinogen, ati gastrin ninu esophagus Barrett.isẹgun ati mofoloji abuda[J].Gastroenterology, 1976, 70 (5 PT.1): 669-676.