Anti- eda eniyan IGFBP-1 Antibody, Mouse Monoclonal
Awọn alaye ọja
Ifihan pupopupo
IGFBP1, tun mọ bi IGFBP-1 ati hisulini-bi idagba ifosiwewe-abuda amuaradagba 1, je egbe kan ti hisulini-bi idagba ifosiwewe-abuda amuaradagba ebi.Awọn ọlọjẹ abuda IGF (IGFBPs) jẹ awọn ọlọjẹ ti 24 si 45 kDa.Gbogbo awọn IGFBP mẹfa pin 50% homology ati pe wọn ni awọn ifaramọ abuda fun IGF-I ati IGF-II ni aṣẹ kanna ti titobi bi awọn ligands ni fun IGF-IR.Awọn ọlọjẹ abuda IGF fa gigun idaji-aye ti awọn IGFs ati pe a ti han lati ṣe idiwọ tabi mu awọn ipa igbega idagbasoke ti awọn IGF lori aṣa sẹẹli.Wọn paarọ ibaraenisepo ti awọn IGF pẹlu awọn olugba oju sẹẹli wọn.IGFBP1 ni agbegbe IGFBP ati agbegbe thyroglobulin iru-I kan.O sopọ mejeeji awọn ifosiwewe idagba bii insulini (IGFs) I ati II ati kaakiri ninu pilasima.Asopọmọra ti amuaradagba yii ṣe gigun ni idaji-aye ti awọn IGF ati ki o ṣe iyipada ibaraenisepo wọn pẹlu awọn olugba oju-ara sẹẹli.
Awọn ohun-ini
| Iṣeduro bata | CLIA (Iwa-iṣawari): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Mimo | > 95% gẹgẹbi ipinnu nipasẹ SDS-PAGE. |
| Ifipamọ Fọọmù | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20 ℃ si -80 ℃ lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Ifiwera Idije
| Bioantibody | Ọran Ayẹwo Isẹgun | Lapapọ | |
| Rere | Odi | ||
| Rere | 35 | 0 | 35 |
| Odi | 1 | 87 | 88 |
| Lapapọ | 36 | 87 | 123 |
| Ni pato | 100% | ||
| Ifamọ | 97% | ||
Bere fun Alaye
| Orukọ ọja | Ologbo.Rara | ID oniye |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
Awọn itọkasi
1.Rutanen EM.Ifosiwewe idagba ti o dabi insulini 1: US 1996.
2.Harman, S, Mitchell, et al.Awọn ipele Serum ti Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, ati Prostate-Pacific Antigen gẹgẹbi Awọn asọtẹlẹ Ile-iwosan Prostate Cancer[J].Iwe akosile ti Clinical Endocrinology & Metabolism, 2000.
