Ifihan pupopupo
Aarun ayọkẹlẹ, tabi aarun ayọkẹlẹ, jẹ akoran ti atẹgun ti o n ran lọwọ nipasẹ ọpọlọpọ awọn ọlọjẹ aisan.Awọn aami aisan ti aisan jẹ pẹlu irora iṣan ati ọgbẹ, orififo, ati iba.Iru kokoro aisan A n yipada nigbagbogbo ati pe o jẹ iduro fun awọn ajakale-arun nla.
Aarun ayọkẹlẹ A le pin si awọn oriṣiriṣi oriṣiriṣi ti o da lori apapo awọn ọlọjẹ meji lori oju-ara gbogun ti: hemagglutinin (H) ati neuraminidase (N).
Iṣeduro bata | IC(Iwa-iwari): 1B5-6 ~ 3A9-8 |
Mimo | > 95%, ipinnu nipasẹ SDS-PAGE |
Ifipamọ Fọọmù | PBS, pH7.4. |
Ibi ipamọ | Tọju rẹ labẹ awọn ipo ifo ni -20℃si -80℃lori gbigba. Ṣeduro lati gbe amuaradagba sinu awọn iwọn kekere fun ibi ipamọ to dara julọ. |
Orukọ ọja | Ologbo.Rara | ID oniye |
Aisan A | AB0023-1 | 1F10-1 |
AB0023-2 | 1B5-6 | |
AB0023-3 | 3A9-8 |
Akiyesi: Bioantibody le ṣe adani awọn iwọn fun iwulo rẹ.
1.Senne DA, Panigrahy B, Kawaoka Y, et al.Iwadi ti hemagglutinin (HA) itọsẹ aaye cleavage ti H5 ati H7 awọn ọlọjẹ aarun ayọkẹlẹ avian: ilana amino acid ni aaye cleavage HA gẹgẹbi ami ti o pọju pathogenicity.[J].Avian Arun, 1996, 40 (2): 425-437.
2.Benton DJ, Gamblin SJ, Rosenthal PB, et al.Awọn iyipada igbekalẹ ni aarun ayọkẹlẹ haemagglutinin ni idapọmọra awo pH[J].Iseda, 2020:1-4.
3.1.Urai C, Wanpen C. Evolution of therapeutic Antibodies, Influenza Virus Biology, Influenza, and Influenza Immunotherapy.Biomed Res Int.2018.
4.2.Florian K. Idahun antibody eniyan si ikolu aarun ayọkẹlẹ A ati ajesara.Iseda agbeyewo ajẹsara.Ọdun 2019, 19, 383-397.